Search on: R 18553 
Descriptors Found: 1
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Descriptor English:   Loperamide 
Descriptor Spanish:   Loperamida 
Descriptor Portuguese:   Loperamida 
Synonyms English:   Hydrochloride, Loperamide
Imodium
Loperamide Hydrochloride
Loperamide Monohydrochloride
Monohydrochloride, Loperamide
R 18553
R-18553
R18553  
Tree Number:   D03.383.621.440
Definition English:   One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. 
Pharmacological Action:   Antidiarrheals
 
History Note English:   91(76); was see under PIPERIDINES 1976-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8314 
Unique Identifier:   D008139 

Occurrence in VHL:
 

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